The biggest man on our list, Chicago Bears defensive end Julius Peppers is not only one of the best defensive linemen in the game, he’s also one of the fastest. Peppers moves his 6'7", 287-pound body around like he’s a lightweight, clocking in on the 40-yard dash in 4.68 seconds. After a few lackluster seasons in Carolina, Peppers has revitalized his career as a member of the bruising Chicago Bears defense by using his rare mixture of strength, speed, size, and raw ability to overpower and outrun his opponents. Imagine trying to block a man his size. Now imagine trying to block a man his size at the speed that Peppers moves. Exactly. Good luck with that.