2. Do I need to update any shots?

Expect your doc to recommend an annual flu shot, and that you get a tetanus booster every 10 years. Otherwise, there may be additional vaccines based on your personal risk profile (family history, lifestyle, etc.) that your doc will suggest, such as the hepatitis B vaccine or the HPV vaccine (see #8).

If you're seeing a new doctor for the first time, know your immunization history before your visit, advises Khatri. If you don’t remember, call your previous doctor’s office.

3. What tests or screens do I need?

As part of an annual or preventive exam, most doctors will order a series of blood tests (such as blood counts, thyroid levels, vitamin B levels, etc.) as well as a blood pressure check. But beyond that, it all depends on your family history and individual risk factors, Khatri says. 

Other risk factors your doc may suggest you act on: family history of diabetes, or early prostate cancer or heart disease.

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4. How often should I get my cholesterol checked?

High cholesterol is one of the first signs you may be at higher risk for heart disease and stroke—and it should not be ignored. American Heart Association guidelines recommend getting your levels checked once every five years, but depending on your numbers and other risk factors, your doc may recommend getting checked more often, says Khatri. "If you're young, healthy, and your cholesterol is great, you probably don't need to be screened for another five years—but if you're borderline and overweight, you may want to get it checked the following year."