To get the most benefits from your morning Joe, leave out the milk and sugar. Better yet, drink espresso. Since it’s prepared under pressure as opposed to regular coffee, all the natural antioxidants and other nutrients are concentrated into each cup of the deep, dark beverage. In moderation, the caffeine is great for helping regulate blood flow and circulation or as a quick energy and mental boost. Aside from giving you an instant pick-me-up, the antioxidants found in the coffee can help boost the immune system and fight off heart disease.