Products containing retinoids are popular amongst women, as the ingredient helps erase wrinkles. The acne-fighting prescription gel Epiduo also contains a retinoid-like compound called adapalene—as well as 2.5% benzoyl peroxide. While the benzoyl peroxide kills the bacteria, the adapalene unclogs all that nastiness inside your pores. “The combination treatment resonates with men, who like to have simple regimens rather than apply multiple products,” says Joel Schlessinger, MD, FAAD, FAACS, of Skin Specialists, P.C. and LovelySkin.com. It also appears to be very effective: Studies have shown that Epiduo can reduce acne by about 18 percent in just the first week.